ASB 14

• ASB-14 is a zwitterionic detergent
• The detergent is a sulfobetaine with a C14 alkyl tail
• Very efficient for solubilizing proteins for 2D analysis
• Optimal solubility achieved in urea-thiourea mixturres and not in urea alone
• Exhibits better solubilization results than CHAPS
• ASB-14 has been shown to solubilize membrane proteins that were previously undetected
• Critical micelle concentration (CMC) 8mM (25C)
• Conductivity <50 microS in a 10% solution

ASB-14 is a zwitterionic detergent
The detergent is a sulfobetaine with a C14 alkyl tail
Very efficient for solubilizing proteins for 2D analysis
Optimal solubility achieved in urea-thiourea mixturres and not in urea alone
Exhibits better solubilization results than CHAPS
ASB-14 has been shown to solubilize membrane proteins that were previously undetected
Critical micelle concentration (CMC) 8mM (25C)
Conductivity <50 microS in a 10% solution