Home > Products > SMPB

SMPB

(Protein Crosslinker heterobifunctional)


CL200   Succinimidyl-4-(p-maleimidophenyl)butyrate
[ 79886-55-8 ]   f.w.: 356.3 daltons

SMPB is an amine to sulfhydryl crosslinker that contains NHS ester and maleimide reactive groups at opposite ends of a medium length aromatic spacer arm (11.6 angstroms).



Quantity Price  
50mgm + $143.00
100mgm + $270.00
Download***Certificate of Analysis***


Spacer arm 14.5 angstroms. Heterobifunctional crosslinker. Conjugates made with SMPB were shown to be more stable in serum than SPDP conjugates. SMPB is a long chain analog of MBS.

  1. Chrisey, L.A., et al. (1996). Nucleic Acids Res. 24(15), 3031-3039. 
  2. Iwai, K., Fukuoka, S.-I., Fushiki, T., Kido, K., Sengoku, Y. and Semba, T. (1988). Preparation of a verifiable peptide-protein immunogen: direction-controlled conjugation of a synthetic fragment of the monitor peptide with myoglobin and application for sequence analysis. Anal. Biochem. 171, 277-282.
  • Extended chain analog of MBS
  • Conjugates formed with SMPB were shown to be more stable in serum than SPDP conjugates
  • Reactive groups: NHS ester and maleimide
  • Reactive towards: amino and sulfhydryl groups