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SULFO GMBS(Protein Crosslinker heterobifunctional) CL227 N-(gamma-Maleimidobutryloxy)sulfosuccinimide esterf.w.: 382.3 daltons |
Sulfo GMBS is a water soluble amine to sulfhydryl crosslinker that contains NHS ester and maleimide reactive groups at opposite ends of a short spacer arm (7.3 angstroms).
| Quantity | Price | |
|---|---|---|
| 50mgm + | $284.00 |  |
| 100mgm + | $536.00 | |
| Download***Certificate of Analysis*** | ||
Spacer arm 6.8 angstroms. Heterobifunctional crosslinker. Sulfonated analog of GMBS, offers water solubility with less immunogenicity. Non-cleavable, membrane impermiable.
- Fujiwara, K., et al. (1988). Sandwich enzyme immunoassay of tumor-associated antigen sialosylated Lewis (x) using beta-D-galactosidase coupled to a monoclonal antibody of IgM isotype. J. Immunol. Meth. 112, 77-83.
- Sulfo GMBS is Non cleavable, membrane impermeable
- It Has a low potential for illiciting crosslinker immune response, ensuring that the primary response to the antigen carrier protein conjugate is not diluted by a response against a determinant on the crosslinker
- GMBS and Sulfo-GMBS are reported to be less immunogenic than SMCC
- Sulfo GMBS has improved solubility in water and aqueous buffer systems
- Reactive groups: maleimide and Sulfo-NHS ester
- Reactive towards: sulfhydryl and amino groups