SULFO GMBS N-(gamma-Maleimidobutyryloxy)sulfosuccinimide ester
Protein Crosslinker heterobifunctional
| Catalog # | CL227 |
|---|---|
| Molecular Formula | C12H11N2O9SNa |
| Formula Weight | f.w.: 382.3 daltons |
Sulfo GMBS is a water soluble amine to sulfhydryl crosslinker that contains NHS ester and maleimide reactive groups at opposite ends of a short spacer arm (7.3 angstroms).
Pricing & Ordering
| Quantity | Price | Action |
|---|---|---|
| 50mgm + | $284.00 |
|
| 100mgm + | $536.00 |
|
Product Documents
Spacer arm 6.8 angstroms. Heterobifunctional crosslinker. Sulfonated analog of GMBS, offers water solubility with less immunogenicity. Non-cleavable, membrane impermiable.
- Fujiwara, K., et al. (1988). Sandwich enzyme immunoassay of tumor-associated antigen sialosylated Lewis (x) using beta-D-galactosidase coupled to a monoclonal antibody of IgM isotype. J. Immunol. Meth. 112, 77-83.
- Sulfo GMBS is Non cleavable, membrane impermeable
- It Has a low potential for illiciting crosslinker immune response, ensuring that the primary response to the antigen carrier protein conjugate is not diluted by a response against a determinant on the crosslinker
- GMBS and Sulfo-GMBS are reported to be less immunogenic than SMCC
- Sulfo GMBS has improved solubility in water and aqueous buffer systems
- Reactive groups: maleimide and Sulfo-NHS ester
- Reactive towards: sulfhydryl and amino groups