SULFO NHS N-Hydroxysulfosuccinimide
| Catalog # | M108 |
|---|---|
| Molecular Formula | C4H4NO6 |
| Formula Weight | f.w.: 217.1 daltons |
N-hydroxysulfosuccinimide (Sulfo NHS) is a chemical modification reagents for converting carboxyl groups to amine reactive Sulfo NHS esters for applications in a variety of bioconjugation and crosslinking methods. Sulfo NHS is the water soluble analog to NHS.
Pricing & Ordering
| Quantity | Price | Action |
|---|---|---|
| 1gm | $296.00 |
|
| 2.5gm + | $735.00 |
|
| 5gm + | $1,399.00 |
|
Product Documents
Protein modification reagent. Used to form amine reactive peptides. The addition of SULFO NHS to carbodiimide mediated coupling reactions results in an increase of hapten carrier protein conjugates.
1.Zhao C. et al. (2010) Effects of a lubricin-containing compound on the results of flexor tendon repair in a canine model in vivo. J. Bone Joint Surg. Am. 92, 1453-61. 2.Anderson G. L. et al. (2010) Assessing lead time of selected ovarian cancer biomarkers: A nested case-control study. J Natl Cancer Inst. 102, 26-38. 3.Ni J. et al. (2009) Plasma protein pentosidine and carboxymethyllysine, biomarkers for age-related macular degeneration. Mol. Cell. Proteomics. 8, 1921-33. 4.Jaetao J. E. et al. (2009) Enhanced leukemia cell detection using a novel magnetic needle and nanoparticles. Cancer Res. 69, 8310-6. 5.Marintcheva B. et al. (2008) Acidic c-terminal tail of the ssdna-binding protein of bacteriophage t7 and ssdna compete for the same binding surface. PNAS. 105, 1855-60.
- Efficiency of EDC mediated coupling is increased in the presence of Sulfo-NHS
- Amine reactive Sulfo NHS esters can be created on any carboxyl containing molecule
- Sulfo NHS derivatives are water soluble, so crosslinking can be done in physiologic solutions
- High purity, crystalline Sulfo NHS can be used to create high purity activated derivatives