BSOCOES(Protein Crosslinker homobifunctional) CL106 Bis[2-(succinimidooxycarbonyloxy)ethyl]sulfonef.w.: 436.4 daltons |
BSOCOES is a homobifunctional NHS ester crosslinker with a base cleavable spacer arm for reversible crosslinking between primary amines.
Spacer arm 13.0 angstroms. Homobifunctional reagent. Cleaveable crosslinker useful for studying receptors and mapping surface polypeptic antigens on lymphocyctes.
1.Bouizar, Z., Fouchereau-Person, M., Taboulet, J., Moukhtar, M.S. and Milhaud, G. (1986). Purification and characterization of calcitonin receptors in rat kidney membranes by covalent crosslinking techniques. Eur. J. Biochem. 155, 141-147. 2.Zarling, D.A., Watson, A. and Bach, F.H. (1980). Mapping of lymphocyte surface polypeptide antigens by chemical crosslinking with BSOCOES. J. Immunol. 124, 913-920.
• Water insoluble • Base cleavable (pH 11.6, 2 hours, 37• C) • Reactive groups: NHS ester (homobifunctional) • Reactive towards: amino groups