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MBS(Protein Crosslinker heterobifunctional) CL202 3-Maleimidobenzoyl-N-hydroxysuccinimide ester[ 58626-38-3 ] f.w.: 314.2 daltons |
MBS is an amine to sulfhydryl crosslinker that contains NHS ester and maleimide reactive groups at opposite ends of a short aromatic spacer arm (7.3 angstroms).
| Quantity | Price | |
|---|---|---|
| 50mgm + | $72.00 |  |
| 100mgm + | $137.00 | |
| Download***Certificate of Analysis*** | ||
Spacer arm 9.9 angstroms. Heterobifunctional crosslinker. A crosslinker that is useful for conjugation of enzymes to antibodies, haptens to carrier proteins and toxins to antibodies. Purity > 95% by TLC. Soluble in DMSO and chloroform.
- Chrisey, L.A., et al. (1996). Nucleic Acids Res. 24(15), 3031-3039.
- Myers, D.E., Uckun, F.M., Swaim, S.E. and Vallera, D.A. (1989). The effects of aromatic and aliphatic maleimide crosslinkers and anti-CD-5 ricin immunotoxins. J. Immunol. Meth. 121, 129-142. (MBS example)
- Kitagawa, T. and Aikawa, T. (1976). Enzyme coupled immunoassay of insulin using a novel coupling reagent. J. Biochem. (Tokyo) 79, 233-236.
•Water insoluble •Non-cleavable •Popular for forming enzyme immunoconjugates •Reactive groups: NHS ester and maleimide •Reactive towards: amino and sulfhydryl groups