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GMBS(Protein Crosslinker heterobifunctional) CL231 N-(beta-Maleimidobutyrloxy)succinimide[ 80307-12-6 ] f.w.: 280.2 daltons |
GMBS is an amine to sulfhydryl crosslinker that contains NHS ester and maleimide reactive groups at opposite ends of a short spacer arm (7.3 angstroms).
| Quantity | Price | |
|---|---|---|
| 50mgm + | $106.00 |  |
| 100mgm + | $200.00 | |
| Download***Certificate of Analysis*** | ||
Spacer arm 6.8 angstroms. Heterobifunctional crosslinker. Analog of MBS, less immunogenic than SMCC. Non cleavable. Low potential for eliciting an immune response ensuring that their primary response to the antigen-carrier protein conjugate is not diluted by a response against a determinant on the crosslinker.
- Chrisey, L.A., et al. (1996). Nucleic Acids Res. 24(15), 3031-3039.
- Fujiwara, K., et al. (1988). Sandwich enzyme immunoassay of tumor-associated antigen sialosylated Lewis (x) using beta-D-galactosidase coupled to a monoclonal antibody of IgM isotype. J. Immunol. Meth. 112, 77-83.
•GMBS has a low potential for eliciting an immune response, ensuring that the primary response is to the antigen-carrier protein conjugate and not against a determinant on the crosslinker •Less immunogenic than SMCC •Reactive groups: NHS ester and maleimide •Reactive toward: amino and sulfhydryl groups