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Fmoc CHLORIDE(Derivatization Reagent) DR113 9-Fluorenylmethylchloroformate[ 28920-43-6 ] f.w.: 256.7 daltons |
A reagent used for the precolumn derivatization of amines for HPLC and fluorescent detection (abs.: 265 nm, em.: 315 nm). Fmoc chloride is used for capillary electrophoresis, deoxyribonucleotide synthesis and is also a precursor for Fmoc protecting reagents for peptide synthesis.
| Quantity | Price | |
|---|---|---|
| 1gm | $25.20 |  |
| 5gm + | $119.00 | |
Base sensitive amino protecting reagent. Used in deoxyribonucleotide synthesis. Also a precursor for Fmoc protecting reagents for peptide synthesis.
1. S. Einarsson et al. Anal. Chem. 58, 1638, (1986) 2. J. Kirschbaum et al. J. Chromatogr. 661, 193, (1994) 3. J.V. Sancho et al. J. Chromatogr. 678, 59, (1994) 4. K.C. Chan et al. J. Chromatogr. 653, 93, (1993) 5. Carpino, L.A. and Han, G.Y., 9-Fluorenylmethoxycarbonyl amino-protecting group J. Org. Chem. 37, 3404, (1972) 6. L.A. Carpino Acc. Chem. Res. 20, 401, (1987) 7. Gioeli, C. and Chattopadhyaya, J.B., The flouren-9-ylmethoxycarbonyl group for the protection of hydroxy-groups; its application in the synthesis of an octathymidylic acid fragment. J. Chem. Soc., Chem. Commun., 672, (1982) 8. Koole, L.H, et al., Synthesis of phosphate-methylated DNA fragments using 9-fluorenylmethoxycarbonyl as transient base protecting group. J. Org. Chem. 54, 1657, (1989)
- Fmoc chloride is a reagent used for the precolumn derivatization of amines for HPLC and fluorescent detection
- Emax = 265nm em 315 nm
- Base sensitive amino protecting reagent
- Used in deoxyribonucleotide synthesis
- Fmoc chloride is a precursor for Fmoc protecting reagents for peptide synthesis