Bolton Hunter SHPP(Iodination Reagent) I101 N-Succinimidyl-3-(4-hydroxyphenyl)propionate[ 3407-95-9 ] f.w.: 236.2 daltons |
Bolton Hunter Reagent conjugates tyrosine like groups to end-terminal ?-amino groups or ?-amino groups of lysine to increase the number of tyrosyl groups that can be iodinated by iodine-125 labeling procedures. Radioactive iodine (iodine-125) is routinely used by researchers to label proteins. The iodination of proteins can be performed enzymatically or chemically. The Bolton-Hunter reagent is designed to aid the labeling of proteins with radioactive iodine.
Iodination reagent. Reacts with N-terminal amino groups at pH 8.5. Iodinate before or after coupling to molecule of interest. Purity > 90%.